Intrapleural Corynebacterium parvum for malignant pleural effusions.
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چکیده
منابع مشابه
Intrapleural Corynebacterium parvum for malignant pleural effusions.
A pilot study of topical (intrapleural) treatment with Corynebacterium parvum was carried out in 10 patients with malignant pleural effusions complicating primary or secondary neoplasms and necessitating frequent thoracocentesis for symptomatic relief. The method was aspiration of all intrapleural fluid except a small portion left for dilution, and then injection of 7 mg of a preparation of Cor...
متن کاملIntrapleural immunotherapy with Corynebacterium parvum in recurrent malignant pleural effusions.
Twenty-one patients with proven recurrent malignant pleural effusions were randomly allocated to treatment groups receiving either intrapleural Corynebacterium parvum in a dose of 7 mg or intrapleural mustine (20 mg). The designated intrapleural therapy was repeated on one occasion if further pleural aspiration was required. Corynebacterium parvum (nine patients) proved superior to mustine (12 ...
متن کاملIntrapleural streptokinase in the management of malignant multiloculated pleural effusions.
OBJECTIVE Pleural effusions are a frequent complication of malignancy and cause considerable morbidity from dyspnea. The drainage and control of malignant effusions relieve symptoms and maintain quality of life but these are difficult in patients with multiloculated effusions in whom drainage usually fails. This observational series reports the use of intrapleural streptokinase (IPSK) in the ma...
متن کاملTreatment of malignant ascitic and pleural effusion with Corynebacterium parvum.
Six patients with malignant effusions, five from adenocarcinomas and one from a melanoma, were treated by intrapleural or intraperitoneal Corynebacterium parvum. In each case there was a definite reduction in the effusions with a significant decrease in the number of malignant cells; in most cases the effusions stopped completely. Although none of the patients lived for more than a year after t...
متن کاملFurther experience of Corynebacterium parvum in malignant pleural effusion.
The outcome of drug induced pleurodesis has been evaluated in a non-randomised retrospective study of 67 patients with recurrent malignant pleural effusions treated during 1976-83. Fourteen died within 30 days of treatment. Of the remaining 53 patients, 26 studied during 1976-80 were treated with intrapleural mustine hydrochloride, while 27 studied during 1978-83 were treated with intrapleural ...
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ژورنال
عنوان ژورنال: Thorax
سال: 1983
ISSN: 0040-6376
DOI: 10.1136/thx.38.1.22